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In the case of carboxyl-bearing molecules, an ester glucuronide is the result. All of these are O-glucuronides. Amines may form N-glucuronides that, unlike O-glucuronides, are resistant to bacterial ?-glucuronidases. Soluble cytoplasmic sulfotransferases conjugate activated sulfate (3’- phosphoadenine-5’-phosphosulfate) with alcohols and phenols.
Structurally, it can be described as a double ACh molecule. Like ACh, succinylcholine acts as agonist at endplate nicotinic cholinoceptors, yet it produces muscle relaxation. Unlike ACh, it is not hydrolyzed by acetylcholinesterase. However, it is a substrate of nonspecific plasma cholinesterase (serum cholinesterase). |
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